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NativeExtract™ Recombinant Full Length Human GBRB3 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW135)

This product is recombinant Human GBRB3 protein in native nanodisc form. The synthetic compound we developed can solubilize the GBRB3 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GBRB3
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 54.1 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • GBRB3
  • Full Name
  • Gamma-Aminobutyric Acid Type A Receptor Beta3 Subunit
  • Introduction
  • This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one the subunits of a multi-subunit chloride channel that serves as the receptor for gamma-aminobutyric acid, a major inhibitory neurotransmitter of the mammalian nervous system. This gene is located on the long arm of chromosome 15 in a cluster with two other genes encoding related subunits of the family. This gene may be associated with the pathogenesis of several disorders including Angelman syndrome, Prader-Willi syndrome, nonsyndromic orofacial clefts, epilepsy and autism. Alternatively spliced transcript variants encoding distinct isoforms have been described.
  • Alternative Names
  • Gamma-Aminobutyric Acid Type A Receptor Beta3 Subunit; Gamma-Aminobutyric Acid (GABA) A Receptor, Beta 3; Gamma-Aminobutyric Acid Receptor Subunit Beta-3; Gamma-Aminobutyric Acid A Receptor Beta 3; GABA-Alpha Receptor Beta-2 Subunit; GABA(A) Receptor Subunit Beta-3

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