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NativeExtract™ Recombinant Full Length Human 5HT3D Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW250)

This product is recombinant Human 5HT3D protein in native nanodisc form. The synthetic compound we developed can solubilize the 5HT3D protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • 5HT3D
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 50.2 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • 5HT3D
  • Full Name
  • 5-Hydroxytryptamine Receptor 3D
  • Introduction
  • The protein encoded this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit D of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a mitogen and a hormone. This hormone has been linked to neuropsychiatric disorders, including anxiety, depression, and migraine. Serotonin receptors causes fast and depolarizing responses in neurons following activation. The genes encoding subunits C, D and E of this type 3 receptor form a cluster on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • 5-Hydroxytryptamine Receptor 3D; 5-Hydroxytryptamine (Serotonin) Receptor 3 Family Member D; 5-Hydroxytryptamine (Serotonin) Receptor 3D, Ionotropic; Serotonin Receptor 3D; 5-Hydroxytryptamine Receptor 3 Subunit D; Serotonin 5-HT-3D Receptor; 5-HT3-D; 5-HT3D; 5HT3D

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