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NativeExtract™ Recombinant Full Length Human CAC1F Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW179)

This product is recombinant Human CAC1F protein in native nanodisc form. The synthetic compound we developed can solubilize the CAC1F protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CAC1F
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 220.7 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • CAC1F
  • Full Name
  • Calcium Voltage-Gated Channel Subunit Alpha1 F
  • Introduction
  • This gene encodes a multipass transmembrane protein that functions as an alpha-1 subunit of the voltage-dependent calcium channel, which mediates the influx of calcium ions into the cell. The encoded protein forms a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Mutations in this gene can cause X-linked eye disorders, including congenital stationary night blindness type 2A, cone-rod dystropy, and Aland Island eye disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed.
  • Alternative Names
  • Calcium Voltage-Gated Channel Subunit Alpha1 F; Calcium Channel, Voltage-Dependent, L Type, Alpha 1F Subunit; Voltage-Gated Calcium Channel Subunit Alpha Cav1.4; Aland Island Eye Disease (Forsius-Eriksson Ocular Albinism, Ocular Albinism Type 2); Voltage-Dependent L-Type Calcium Channel Subunit Alpha-1F; Cav1.4alpha1; CACNAF1; CORDX3; CSNB2A; CSNBX2

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