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NativeExtract™ Recombinant Full Length Human GLRA1 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW101)

This product is recombinant Human GLRA1 protein in native nanodisc form. The synthetic compound we developed can solubilize the GLRA1 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GLRA1
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 52.6 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • GLRA1
  • Full Name
  • Glycine Receptor Alpha 1
  • Introduction
  • The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor, which mediates postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Multiple transcript variants encoding different isoforms have been found.
  • Alternative Names
  • Glycine Receptor Alpha 1; Glycine Receptor Strychnine-Binding Subunit; Glycine Receptor 48 KDa Subunit; Glycine Receptor, Alpha 1 (Startle Disease/Hyperekplexia); Glycine Receptor Subunit Alpha-1; Stiff Person Syndrome; HKPX1; STHE

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