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NativeExtract™ Recombinant Full Length Human BACD1 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW166)

This product is recombinant Human BACD1 protein in native nanodisc form. The synthetic compound we developed can solubilize the BACD1 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • BACD1
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 36.4 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • BACD1
  • Full Name
  • Potassium Channel Tetramerization Domain Containing 13
  • Introduction
  • Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for synaptic transmission (PubMed:19782033). The BCR(KCTD13) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome (PubMed:19782033) Degradation of RHOA regulates the actin cytoskeleton and promotes synaptic transmission (By similarity).
  • Alternative Names
  • Potassium Channel Tetramerization Domain Containing 13; Polymerase Delta-Interacting Protein 1; Potassium Channel Tetramerisation Domain Containing 13; BTB/POZ Domain-Containing Protein KCTD13; TNFAIP1-Like Protein; HBACURD1; BACURD1

Case Studies

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