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NativeExtract™ Recombinant Full Length Human GRIK3 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW125)

This product is recombinant Human GRIK3 protein in native nanodisc form. The synthetic compound we developed can solubilize the GRIK3 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GRIK3
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 104.0 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • GRIK3
  • Full Name
  • Glutamate Ionotropic Receptor Kainate Type Subunit 3
  • Introduction
  • Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics.
  • Alternative Names
  • Glutamate Ionotropic Receptor Kainate Type Subunit 3; Excitatory Amino Acid Receptor 5; Glutamate Receptor 7; GluR-7; GLUR7; GluK3; EAA5

Case Studies

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