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NativeExtract™ Recombinant Full Length Human KCAB2 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW239)

Datasheet
This product is recombinant Human KCAB2 protein in native nanodisc form. The synthetic compound we developed can solubilize the KCAB2 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KCAB2
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 41 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • KCAB2
  • Full Name
  • Potassium Voltage-Gated Channel Subfamily A Regulatory Beta Subunit 2
  • Introduction
  • Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member alters functional properties of the KCNA4 gene product. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
  • Alternative Names
  • Potassium Voltage-Gated Channel Subfamily A Regulatory Beta Subunit 2; Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Beta Member 2; Potassium Channel, Voltage Gated Subfamily A Regulatory Beta Subunit 2; K(+) Channel Subunit Beta-2; KV-BETA-2; HKvbeta2; KCNA2B

Case Studies

Customer reviews and Q&As    

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