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NativeExtract™ Recombinant Full Length Human HRH3 Protein (Nanodisc, FLAG-tagged) (CAT#: SYF-0426-CW3)

This product is recombinant Human HRH3 protein in native nanodisc form. The synthetic compound we developed can solubilize the HRH3 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • HRH3
  • Protein Length
  • Full length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 48.7 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • HRH3
  • Full Name
  • Histamine Receptor H3
  • Introduction
  • Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system.
  • Alternative Names
  • HH3R; GPCR97

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