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NativeExtract™ Recombinant Full Length Human TPC1 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW53)

This product is recombinant Human CXG1 protein in native nanodisc form. The synthetic compound we developed can solubilize the CXG1 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TPC1
  • Protein Length
  • Full length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 94.1 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • TPC1
  • Full Name
  • Two Pore Segment Channel 1
  • Introduction
  • Voltage-gated Ca(2+) and Na+ channels have 4 homologous domains, each containing 6 transmembrane segments, S1 to S6. TPCN1 is similar to these channels, but it has only 2 domains containing S1 to S6 (Ishibashi et al., 2000 ).[supplied by OMIM, Mar 2008]
  • Alternative Names
  • Two Pore Segment Channel 1; Voltage-Dependent Calcium Channel Protein TPC1; TPC1; Two Pore Calcium Channel Protein 1; Two-Pore Channel 1, Homolog; KIAA1169

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