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NativeExtract™ Recombinant Full Length Human P2RX3 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW86)

This product is recombinant Human P2RX3 protein in native nanodisc form. The synthetic compound we developed can solubilize the P2RX3 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • P2RX3
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 44.3 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • P2RX3
  • Full Name
  • Purinergic Receptor P2X 3
  • Introduction
  • This gene encodes a member of the P2X purinergic receptor (purinoceptor) gene family which includes seven members (P2RX1 - P2RX7). P2X purinoceptors are a family of cation-permeable, ligand-gated ion channels that open in response to the binding of extracellular adenosine 5'-triphosphate (ATP). The encoded protein is a subunit of the trimeric P2X3 receptor ion channel which is expressed by sensory or autonomic neurons. A deficiency of the orthologous protein in mice is associated with reduced pain-related behavior and urinary bladder hyporeflexia.
  • Alternative Names
  • Purinergic Receptor P2X 3; ATP Receptor; P2X3; Purinergic Receptor P2X, Ligand-Gated Ion Channel, 3; Purinergic Receptor P2X, Ligand Gated Ion Channel, 3; Purinergic Receptor P2X3

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