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NativeExtract™ Recombinant Full Length Human GBRE Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW73)

This product is recombinant Human GBRE protein in native nanodisc form. The synthetic compound we developed can solubilize the GBRE protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GBRE
  • Protein Length
  • Full length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 58 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • GBRE
  • Full Name
  • Gamma-Aminobutyric Acid Type A Receptor Epsilon Subunit
  • Introduction
  • The product of this gene belongs to the ligand-gated ionic channel (TC 1.A.9) family. It encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes an epsilon subunit. It is mapped to chromosome Xq28 in a cluster comprised of genes encoding alpha 3, beta 4 and theta subunits of the same receptor. Alternatively spliced transcript variants have been identified, but only one is thought to encode a protein.
  • Alternative Names
  • Gamma-Aminobutyric Acid Type A Receptor Epsilon Subunit; Gamma-Aminobutyric Acid (GABA) A Receptor, Epsilon; GABA(A) Receptor Subunit Epsilon; GABA(A) Receptor, Epsilon

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