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NativeExtract™ Recombinant Full Length Human SCN4A Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW160)

This product is recombinant Human SCN4A protein in native nanodisc form. The synthetic compound we developed can solubilize the SCN4A protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SCN4A
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 208.1 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • SCN4A
  • Full Name
  • Sodium Voltage-Gated Channel Alpha Subunit 4
  • Introduction
  • Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. It is expressed in skeletal muscle, and mutations in this gene have been linked to several myotonia and periodic paralysis disorders.
  • Alternative Names
  • Sodium Voltage-Gated Channel Alpha Subunit 4; Sodium Channel, Voltage-Gated, Type IV, Alpha Subunit; Sodium Channel Protein Skeletal Muscle Subunit Alpha; Voltage-Gated Sodium Channel Subunit Alpha Nav1.4; Sodium Channel Protein Type IV Subunit Alpha; SkM1; Skeletal Muscle Voltage-Dependent Sodium Channel Type IV Alpha Subunit; Sodium Channel, Voltage Gated, Type IV Alpha Subunit; Skeletal Muscle Sodium Channel Alpha Subunit; Sodium Channel Protein Type 4 Subunit Alpha

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