Discovery
- Services
  Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
  Highlights
  - Discovery Services
  - Engineering Services
Characterization
- Services
  Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
  Highlights
  - Discovery Services
  - Engineering Services
Engineering
- Services
  Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
  Highlights
  - Discovery Services
  - Engineering Services
Custom Production & Manufacturing
- - Custom Production
    
    Membrane Protein Preparation
    
    GPCR Preparation
    
    Ion Channel Preparation
    
    Transporter Preparation
    
    Custom Membrane Protein Production
    
    Custom Membrane Protein Solubilization & Stabilization
    
    Custom Membrane Protein QC
    
    Virus Like Particle Production
    
    Insect Cell based VLP Production
    
    Mammalian Cell based VLP Production
    
    E. coli based VLP Production
    
    Yeast Cell based VLP Production
    
    Plant Cell based VLP Production
    
    Recombinant Antibody Production
    
    Ascite Fluid based Antibody Production
    
    Stable Cell Line Construction
  - Manufacturing
    
    Manufacturability Assessment & Optimization
    
    Virtual Prediction
    
    Amino Acid & Terminal Sequence Analysis
- Services
  Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
  Highlights
  - Discovery Services
  - Engineering Services
Products
- Products
  With over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications.
Platforms
- Platforms
  Creative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
  Highlights
  - B-Cell Sorting Platform
  - Phage Display Platform
Resources
- Resources
  With deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
  Highlights
  - Peer-Reviewed Publications
  - Support Documents
Company
- About Us
  Get a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
  Highlights
  - About Us
  - Contact Us

Product Service Keyword

Online Inquiry

	: : :
	Call us at: : : :
	Fax:
	Email:

NativeExtract™ Recombinant Full Length Human SCN5A Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW159)

Name: NativeExtract™ Recombinant Full Length Human SCN5A Protein (Nanodisc, FLAG- & Strep-tagged)
SKU: SYF-0426-CW159
Rating: 5 (1 reviews)

Datasheet

This product is recombinant Human SCN5A protein in native nanodisc form. The synthetic compound we developed can solubilize the SCN5A protein from membrane while retaining the native structure.

Product Specifications

Host Species
Human

Target Protein
SCN5A

Protein Length
Full length

Protein Class
Ion Channel

Molecular Weight
226.9 kDa

Sequence
Accession #Q14524

Product Description

Activity
Yes

Application
ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays

Expression Systems
HEK293 expression system

Tag
The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.

Protein Format
Nanodisc

Buffer
20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

Target Protein
SCN5A

Full Name
Sodium Voltage-Gated Channel Alpha Subunit 5

Introduction
The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms.

Alternative Names
Sodium Voltage-Gated Channel Alpha Subunit 5; Sodium Channel, Voltage-Gated, Type V, Alpha Subunit; Sodium Channel Protein Cardiac Muscle Subunit Alpha; Voltage-Gated Sodium Channel Subunit Alpha Nav1.5; HH1; Cardiac Tetrodotoxin-Insensitive Voltage-Dependent Sodium Channel Alpha Subunit; Sodium Channel, Voltage-Gated, Type V, Alpha (Long QT Syndrome 3); Sodium Channel, Voltage Gated, Type V Alpha Subunit; Sodium Channel Protein Type 5 Subunit Alpha; Sodium Channel Protein Type V Subunit Alpha; Long QT Syndrome 3; Nav1.5; PFHB1

Gene ID
6331

UniProt ID
Q14524

Case Studies

Customer reviews and Q&As Write a review Ask a question

Related Products

CAT
Product Name