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MemDX™ Recombinant Full Length Human SLC25A37 Protein (Biotinylated Nanodisc, Rho1D4 Tag) (CAT#: SYF-0926-CW181)

Recombinant full-length human SLC25A37 protein reconstituted in a biotinylated nanodisc membrane-mimetic system for immobilization, binding, detection, and assay development applications; the copolymer is biotinylated while the protein itself remains unmodified.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SLC25A37
  • Protein Length
  • Full-length
  • Protein Class
  • Mitochondrial Carrier
  • Molecular Weight
  • 38 kDa
  • Sequence
  • MELRSGSVGSQAVARRMDGDSRDGGGGKDATGSEDYENLPTSASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRAPY

Product Description

  • Expression Systems
  • HEK293 cells
  • Tag
  • The construct includes a C-terminal Rho1D4 tag. The copolymer is biotinylated; the protein itself is unmodified.
  • Protein Format
  • Nanodisc
  • Purity
  • The protein purity is greater than 90% as determined by SDS-PAGE.

Target

  • Target Protein
  • SLC25A37
  • Full Name
  • solute carrier family 25 member 37
  • Introduction
  • Mitoferrin-1 (SLC25A37) is a full-length human slc transporter. SLC25A37 (Mitoferrin-1) functions as the essential mitochondrial iron importer required for heme biosynthesis and iron-sulfur cluster assembly, particularly during red blood cell development. Therapeutically, targeting this transporter offers novel strategies to treat anemias and tissue ischemia by managing iron overload, or to combat aggressive cancers by disrupting their metabolic dependency on iron and modulating ferroptosis. The surrounding nanodisc copolymer is biotinylated to support direct surface immobilization without modifying the protein itself. The preparation uses 2-step purification.
  • Alternative Names
  • MSCP, MFRN, MFRN1, HT015

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