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NativeExtract™ Recombinant Full Length Human KCMB4 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW218)

This product is recombinant Human KCMB4 protein in native nanodisc form. The synthetic compound we developed can solubilize the KCMB4 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KCMB4
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 23.9 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • KCMB4
  • Full Name
  • Potassium Calcium-Activated Channel Subfamily M Regulatory Beta Subunit 4
  • Introduction
  • MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which slows activation kinetics, leads to steeper calcium sensitivity, and shifts the voltage range of current activation to more negative potentials than does the beta 1 subunit.
  • Alternative Names
  • Potassium Calcium-Activated Channel Subfamily M Regulatory Beta Subunit 4; Potassium Large Conductance Calcium-Activated Channel, Subfamily M, Beta Member 4; Calcium-Activated Potassium Channel, Subfamily M Subunit Beta-4; Potassium Channel Subfamily M Regulatory Beta Subunit 4; Charybdotoxin Receptor Subunit Beta-4; Big Potassium Channel Beta Subunit 4; Maxi K Channel Subunit Beta-4; MaxiK Channel Beta-Subunit 4; BK Channel Beta Subunit 4

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