B7-2

B7-2 is a protein expressed on antigen-presenting cells that provides costimulatory signals necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 (for autoregulation and intercellular association) and CTLA-4 (for attenuation of regulation and cellular disassociation). CD86 works in tandem with CD80 to prime T cells. Its gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-3476Lsx Recombinant Rat B7-2 Protein HEK293 Cells Recombinant Rat B7-2 (CD86) Protein, expressed in HEK293 Cells. (NCBI ID: 56822) B7-2 Tumor Antigens Datasheet 50 µg Inquiry
VAng-3477Lsx Recombinant Mouse B7-2 Protein (aa 26-245) [Fc] HEK293 Cells Recombinant Mouse B7-2 (CD86) Protein, expressed in HEK293 Cells. (Uniprot ID: P42082) B7-2 Tumor Antigens Datasheet 10 µg Inquiry
VAng-3478Lsx Recombinant Rat B7-2 Protein (aa 29-247) [His] HEK293 Cells Recombinant Rat B7-2 (CD86) Protein, expressed in HEK293 Cells. (NCBI ID: O35531) B7-2 Tumor Antigens Datasheet 50 µg Inquiry
VAng-3479Lsx Recombinant Mouse B7-2 Protein [His] HEK293 Cells Recombinant Mouse B7-2 (CD86) Protein, expressed in HEK293 Cells. (Uniprot ID: P42082) B7-2 Tumor Antigens Datasheet 10 µg Inquiry
VAng-3480Lsx Recombinant Human B7-2 Protein [His] [Fc] HEK293 Cells Recombinant Human B7-2 (CD86) Protein, expressed in HEK293 Cells. (Uniprot ID: P42081) B7-2 Tumor Antigens Datasheet 100 µg Inquiry

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