In silico Vaccine Design
Infectious diseases caused by bacteria, viruses, fungi, and parasites cause millions of deaths worldwide every year. The efficacy of all known current anti-infective agents is affected by the drug resistant form of the pathogens. Therefore, the development of anti-infective drugs that target drug-resistant pathogens is very urgent. In silico models help to understand infectious diseases and develop novel therapeutics to treat them. Creative Biolabs offers in silico service to predict and design new vaccine and vaccine components.
Databases and in Silico Models for Vaccine Design
With the advent of computer-aided informatics and high-throughput technologies, vaccine research has entered a new era. Rational vaccine prediction is more reasonable than years ago because of the two progressive areas, vaccine database and in silico vaccine design models.
In silico models and databases play different but complementary roles in vaccine design. The database collects information about experimentally verified vaccine and vaccine components and in silico models use computational methods to predict and design new vaccine and the components.
In the development of small molecules, in silico model is important in genome-wide analysis, comparative genomics, pathway analysis, virtual screening and target identification. For vaccine development, in silico model can accelerate the computer identification algorithm of the relevant protein candidates with improved expression immunogens.
Advanced DNA sequencing and cellular, molecular and immunological methods provide a large number of vaccine-related data, which has led to an increase in the amount of data associated with vaccines and vaccinations. Advanced bioinformatics tools have been developed to make effective use of these data and vaccine-related papers has increased exponentially since then. Databases that store, reorganize, and classify these data, promote the discovery of vaccine. Vaccine discovery, in turn, support the accumulation of vaccine data more efficiently in the database.
A variety of in silico models for vaccine design have been developed to predict T-cells and B-cell immune epitopes. After predicting candidate proteins, high-throughput assays can be used to evaluate efficacy of the vaccine.
Our Services
In terms of our abundant experience, Creative Biolabs can offer advanced in silico vaccine design service to support lead candidate selection and rational design for vaccines.
Features
- Cost-effective and time-saving
- High throughput applicable
- Analyze and provide advice on vaccine design
- Increase chances of success vaccines
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
