Gastrointestinal Cancers

Creative Biolabs is a world leader in the field of cancer vaccine development. With our extensive experience and advanced platform, we are therefore confident in offering the best vaccine development services for different types of gastrointestinal cancers including Esophageal Cancer, Gastric Cancer, Pancreatic Cancer, Liver Cancer, Gallbladder Cancer, Cholangiocarcinoma, Colorectal Cancer and Anal Cancer. We guarantee the finest results for our customers all over the world.

Gastrointestinal cancer refers to the malignant conditions of the gastrointestinal tract and digestive glands, including the esophagus, stomach, biliary tract, pancreas, small intestine, large intestine, rectum, and anus. Symptoms involving the affected organ may include abnormal bleeding, obstruction (resulting in difficulty swallowing or defecation), or other related problems. Diagnosis usually requires endoscopy, followed by biopsy of suspicious tissue. Treatment depends on the location of the tumor, the type of cancer cells, and whether it has intruded into other part of the body. These factors also determine the prognosis. In general, the gastrointestinal tract and accessory organs of the digestive (liver, pancreas, gallbladder) are responsible for more cancers and more likely to die of cancer than any other system of the body.

Esophageal Cancer

Esophageal cancer is the sixth-most-common cancer in the world. It is a type of cancer arising from the esophagus, a food pipe runs between the throat and stomach. There are two main types of esophageal cancer—squamous cell carcinoma and adenocarcinoma. The most common causes of adenocarcinoma type include obesity, smoking, and acid reflux. Some of the less common types include squamous cell carcinomas from esophageal epithelial cells.

Gastric Cancer - Creative Biolabs

Gastric Cancer

Gastric cancer, also known as stomach cancer, is the fourth-most-common type of cancer and the second-highest cause of cancer death globally. The most common cause is Helicobacter pylori infection, accounting for more than 60% of all cases. Other risk factors include smoking, dietary factors such as pickles vegetables and obesity. Early symptoms may include nausea, loss of appetite, heartburn and upper abdominal pain. Later signs and symptoms may include vomiting, weight loss, difficulty swallowing, yellowing of the skin and whites of the eyes as well as hematochezia. Chemotherapy improves survival compared to best supportive care, however, the optimal regimen is unclear.

Pancreatic Cancer

Pancreatic cancer is the fifth-most-common cause of cancer deaths in the United States. It is a type of cancer arising from cells in the pancreas (a glandular organ behind the stomach) when they begin to run out of control and become lumps. These cancers are classified as endocrine or nonendocrine tumors. The most common is ductal adenocarcinoma.

Liver Cancer

People get liver cancer (also called hepatocellular carcinoma, HCC or hepatoma) typically from a prolonged Hepatitis B or C infection or as a result of cirrhosis from chronic alcoholism. Liver cancer is a major health problem, with more than 850,000 new cases annually worldwide. Treatments that have been shown to extend the life expectancy of patients with HCC include surgical resection, liver transplantation, radiofrequency ablation, chemoembolization, and the multi-kinase inhibitor sorafenib.

Gallbladder Cancer

Cancers of the gallbladder are typically adenocarcinomas and are common in elderly women. It is thought to be associated with the building up of gallstones and may also cause gallbladder calcification, a situation known as porcelain gall bladder, which is also rare. Gallbladder cancer is strongly associated with gallstones, a porcelain gallbladder appearance on ultrasound, and the presence of polyps within the gallbladder. Gallbladder cancer may manifest with jaundice, weight loss, and pain in the upper right of. If diagnosed early, it can be cured by resection of the gallbladder, part of the liver, and the associated lymph nodes. It is mostly found after abdominal pain, jaundice and vomiting and other symptoms, and has already spread to the liver and other organs.

Gastrointestinal System - Creative Biolabs

Cholangiocarcinoma

Cholangiocarcinoma, also known as bile duct cancer, is a type of cancer consisting of a mutant epithelial cell (or a cell that exhibits epithelial differentiation). It originates in the bile ducts that excrete bile from the liver into the small intestine. The obvious signs and symptoms of cholangiocarcinoma include jaundice, abdominal pain, abnormal liver function tests and weight loss. Since primary tumors and any metastases are less likely to be fully removed by surgery, cholangiocarcinoma is considered to be an incurable and rapidly fatal cancer. There is no potential curative treatment other than surgery.

Colorectal Cancer

Colorectal cancer (CRC), also known as colon cancer and bowel cancer, is a disease of old age which typically originates in the secretory cells lining the gut. Most colorectal cancers are due to aging and lifestyle factors and only a minority of cases are due to underlying genetic disorders. Some of the risk factors include smoking, obesity, diet and lack of exercise. Use of a colonoscope can find these cancers, and a biopsy can reveal the extent of the involvement of the bowel wall. Treatments for colorectal cancer may include some combination of surgery, radiotherapy, chemotherapy and targeted therapies.

Anal Cancer

Anal cancer is strongly associated with ulcerative colitis and the sexually transmissible infections HPV and HIV. It is a type of cancer developed from the anus, which is the distal opening of the gastrointestinal tract. It is a different entity from the more common colorectal cancer. Symptoms of anal cancer include itching or bleeding in the rectum, pain or pressure in the anus or rectum, changes in bowel habits, and lumps in the vicinity of the anus. Anal cancer is investigated by biopsy and may be treated by excision and radiotherapy, or with external beam radiotherapy and adjunctive chemotherapy.

Creative Biolabs is a leader in the field of vaccine development and has focused on the cancer vaccines for years. We have experts who are able to help you with the vaccine development for different types of gastrointestinal cancers. If you are interested in our services, please contact us for more details.


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