B7-H4

B7-H4 is a protein that in humans is encoded by B7-H4 gene. B7-H4 belongs to the B7 family of costimulatory proteins. These proteins are expressed on the surface of antigen-presenting cells and interact with ligands (CD28) on T lymphocytes. It inhibits T cell proliferation and cytokine production through ligation of an unknown receptor expressed by activated T cells. Notably, B7-H4 protein expression is observed in a high proportion of patients' tumors across a wide variety of malignancies. This high expression by tumors in combination with its low or absent protein expression in normal tissues makes B7-H4 an attractive immunotherapeutic target.

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-3528Lsx Recombinant Human B7-H4 Protein (aa 25-259) (Baculovirus) Baculovirus Recombinant Human B7-H4 Protein, expressed in Baculovirus. (Uniprot ID: Q7Z7D3) B7-H4 Tumor Antigens Datasheet 50 µg Inquiry
VAng-3529Lsx Recombinant Human B7-H4 Protein (aa 25-259) (Mammalian-Cell) Mammalian Cells Recombinant Human B7-H4 Protein, expressed in Mammalian Cells. (Uniprot ID: Q7Z7D3) B7-H4 Tumor Antigens Datasheet 50 µg Inquiry
VAng-3530Lsx Recombinant Human B7-H4 Protein (aa 25-259) (E. coli) [His] E. coli Recombinant Human B7-H4 Protein, expressed in E. coli. (Uniprot ID: Q7Z7D3) B7-H4 Tumor Antigens Datasheet 500 µg Inquiry
VAng-3531Lsx Recombinant Human B7-H4 Protein (aa 25-259) (Baculovirus) [His] Baculovirus Recombinant Human B7-H4 Protein, expressed in Baculovirus. (Uniprot ID: Q7Z7D3) B7-H4 Tumor Antigens Datasheet 50 µg Inquiry
VAng-3532Lsx Recombinant Human B7-H4 Protein (aa 34-147) [His] E. coli Recombinant Human B7-H4 Protein, expressed in E. coli. (Uniprot ID: Q7Z7D3) B7-H4 Tumor Antigens Datasheet 200 µg Inquiry
VAng-3533Lsx Recombinant Human B7-H4 Protein (aa 153-241) [His] [GST] E. coli Recombinant Human B7-H4 Protein, expressed in E. coli. (Uniprot ID: Q7Z7D3) B7-H4 Tumor Antigens Datasheet 200 µg Inquiry

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