CA 15-3
CA 15-3 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and several other organs. Mucins protect the body from infection by pathogen binding to oligosaccharides in the extracellular domain, preventing the pathogen from reaching the cell surface. Overexpression of MUC1 is often associated with colon, breast, ovarian, lung and pancreatic cancers. The protein is anchored to the apical surface of many epithelia by a transmembrane domain. Beyond the transmembrane domain is a SEA domain that contains a cleavage site for release of the large extracellular domain. The release of mucins is performed by sheddases.| CAT | Product Name | Source | Product Overview | Target | Type | Datasheet | Size | Price |
|---|---|---|---|---|---|---|---|---|
| VAng-3932Lsx | Recombinant Human MUC1 Protein (aa 24-273) (E. coli) | E. coli | Recombinant Human Mucin-1 (MUC1) protein, expressed in E. coli. (Uniprot ID: P15941) | CA 15-3 | Tumor Antigens |  |
200 µg | Inquiry |
| VAng-3933Lsx | Recombinant Human MUC1 Protein (aa 1098-1255) [His] | E. coli | Recombinant Human Mucin-1 (MUC1) protein, expressed in E. coli. (Uniprot ID: P15941) | CA 15-3 | Tumor Antigens | |
200 µg | Inquiry |
| VAng-3934Lsx | Recombinant Human MUC1 Protein (aa 23-167) [Fc] | HEK293 Cells | Recombinant Human Mucin-1 (MUC1) protein, expressed in HEK293 Cells. (Uniprot ID: P15941) | CA 15-3 | Tumor Antigens | |
10 µg | Inquiry |
| VAng-3935Lsx | Recombinant Mouse MUC1 Protein (aa 410-525) [His] [GST] | E. coli | Recombinant Mouse Mucin-1 (MUC1) protein, expressed in E. coli. (Uniprot ID: Q60528) | CA 15-3 | Tumor Antigens | |
200 µg | Inquiry |
| VAng-3936Lsx | Recombinant Rat MUC1 Protein (aa 25-349) [His] [GST] [S] | E. coli | Recombinant Rat Mucin-1 (MUC1) protein, expressed in E. coli. (Uniprot ID: Q60528) | CA 15-3 | Tumor Antigens | |
200 µg | Inquiry |
| VAng-3937Lsx | Recombinant Mouse MUC1 Protein (aa 474-630) [His] [GST] | E. coli | Recombinant Mouse Mucin-1 (MUC1) protein, expressed in E. coli. (Uniprot ID: Q60528) | CA 15-3 | Tumor Antigens | |
200 µg | Inquiry |
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
