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NativeExtract™ Recombinant Full Length Human 5HT3B Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW176)

This product is recombinant Human 5HT3B protein in native nanodisc form. The synthetic compound we developed can solubilize the 5HT3B protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • 5HT3B
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 50.3 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • 5HT3B
  • Full Name
  • 5-Hydroxytryptamine Receptor 3B
  • Introduction
  • The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It is not functional as a homomeric complex, but a pentaheteromeric complex with subunit A (HTR3A) displays the full functional features of this receptor.
  • Alternative Names
  • 5-Hydroxytryptamine Receptor 3B; 5-Hydroxytryptamine (Serotonin) Receptor 3B, Ionotropic; 5-HT3-B; 5-HT3B; 5-Hydroxytryptamine (Serotonin) Receptor 3B; 5-Hydroxytryptamine 3 Receptor B Subunit; Serotonin-Gated Ion Channel Subunit; Serotonin Receptor 3B

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