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NativeExtract™ Recombinant Full Length Human NMDE3 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW140)

Datasheet
This product is recombinant Human NMDE3 protein in native nanodisc form. The synthetic compound we developed can solubilize the NMDE3 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • NMDE3
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 134.2 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • NMDE3
  • Full Name
  • Glutamate Ionotropic Receptor NMDA Type Subunit 2C
  • Introduction
  • This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptor, which is a subtype of ionotropic glutamate receptor. NMDA receptors are found in the central nervous system, are permeable to cations and have an important role in physiological processes such as learning, memory, and synaptic development. The receptor is a tetramer of different subunits (typically heterodimer of subunit 1 with one or more of subunits 2A-D), forming a channel that is permeable to calcium, potassium, and sodium, and whose properties are determined by subunit composition. Alterations in the subunit composition of the receptor are associated with pathophysiological conditions such as Parkinson's disease, Alzheimer's disease, depression, and schizophrenia. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • Glutamate Ionotropic Receptor NMDA Type Subunit 2C; Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2C; Glutamate [NMDA] Receptor Subunit Epsilon-3; N-Methyl D-Aspartate Receptor Subtype 2C; NMDAR2C; GluN2C; NR2C; N-Methyl-D-Aspartate Receptor Subunit 2C; Glutamate Receptor Ionotropic, NMDA 2C

Case Studies

Customer reviews and Q&As    

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