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MemDX™ Recombinant Full Length Human AQP1 Protein (Biotinylated Nanodisc, Rho1D4 Tag) (CAT#: SYF-0926-CW41)

Datasheet
Recombinant full-length human AQP1 protein reconstituted in a biotinylated nanodisc membrane-mimetic system for immobilization, binding, detection, and assay development applications; the copolymer is biotinylated while the protein itself remains unmodified.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • AQP1
  • Protein Length
  • Full-length
  • Protein Class
  • Aquaporin
  • Molecular Weight
  • 29 kDa (homotetramer)
  • Sequence
  • MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTDRVKVWTSGQVEEYDLDADDINSRVEMKPK

Product Description

  • Expression Systems
  • HEK293 cells
  • Tag
  • The construct includes a C-terminal Rho1D4 tag. The copolymer is biotinylated; the protein itself is unmodified.
  • Protein Format
  • Nanodisc
  • Purity
  • The protein purity is greater than 90% as determined by SDS-PAGE.

Target

  • Target Protein
  • AQP1
  • Full Name
  • aquaporin 1
  • Introduction
  • Aquaporin-1 (AQP1) is a full-length human aquaporin. Aquaporin-1 is a protein involved in water homeostasis in several tissues by forming a water channel that allows passive transport of water along the osmotic gradient. It is implicated in the inter- and intracellular transport of water and is mainly expressed in the kidney. AQP1 may be associated with various health conditions, such as ocular fluid movement, but it could also be a prognostic marker for various types of cancer, as AQP1 has been shown to regulate tumour cell migration, cell-cell adhesion and angiogenesis, among other things, and is thus involved in cancer progression. The surrounding nanodisc copolymer is biotinylated to support direct surface immobilization without modifying the protein itself. The preparation uses 2-step purification.
  • Alternative Names
  • CHIP28, CO

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