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NativeExtract™ Recombinant Full Length Human P2RX6 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW88)

This product is recombinant Human P2RX6 protein in native nanodisc form. The synthetic compound we developed can solubilize the P2RX6 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • P2RX6
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 48.8 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • P2RX6
  • Full Name
  • Purinergic Receptor P2X 6
  • Introduction
  • The protein encoded by this gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 22, has been identified.
  • Alternative Names
  • Purinergic Receptor P2X 6; Purinergic Receptor P2X-Like 1, Orphan Receptor; ATP Receptor; P2RXL1; P2X6; P2XM; Purinergic Receptor P2X, Ligand-Gated Ion Channel, 6; Purinergic Receptor P2X, Ligand Gated Ion Channel, 6

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