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NativeExtract™ Recombinant Full Length Human CLCN5 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW112)

Datasheet
This product is recombinant Human CLCN5 protein in native nanodisc form. The synthetic compound we developed can solubilize the CLCN5 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CLCN5
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 83.1 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • CLCN5
  • Full Name
  • Chloride Voltage-Gated Channel 5
  • Introduction
  • This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.
  • Alternative Names
  • Chloride Voltage-Gated Channel 5; Chloride Channel, Voltage-Sensitive 5; Chloride Transporter ClC-5; CLCK2; ClC-5; Voltage-Gated Chloride Ion Channel CLCN5; H(+)/Cl(-) Exchange Transporter 5; Nephrolithiasis 1 (X-Linked); Nephrolithiasis 2, X-Linked; Chloride Channel Protein 5

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Customer reviews and Q&As    

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