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NativeExtract™ Recombinant Full Length Human KCAB1 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW240)

Datasheet
This product is recombinant Human KCAB1 protein in native nanodisc form. The synthetic compound we developed can solubilize the KCAB1 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KCAB1
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 46.6 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • KCAB1
  • Full Name
  • Potassium Voltage-Gated Channel Subfamily A Member Regulatory Beta Subunit 1
  • Introduction
  • Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes distinct isoforms which are encoded by alternatively spliced transcript variants of this gene. Some of these isoforms are beta subunits, which form heteromultimeric complexes with alpha subunits and modulate the activity of the pore-forming alpha subunits.
  • Alternative Names
  • Potassium Voltage-Gated Channel Subfamily A Member Regulatory Beta Subunit 1; Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Beta Member 1; K(+) Channel Subunit Beta-1; K+ Channel Beta1a Chain; KV-BETA-1; KCNA1B; Potassium Channel, Voltage Gated Subfamily A Regulatory Beta Subunit 1; Voltage-Gated Potassium Channel Subunit Beta-1; Potassium Channel Shaker Chain Beta 1a

Case Studies

Customer reviews and Q&As    

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