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NativeExtract™ Recombinant Full Length Human KCNH2 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW126)

This product is recombinant Human KCNH2 protein in native nanodisc form. The synthetic compound we developed can solubilize the KCNH2 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KCNH2
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 126.7 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • KCNH2
  • Full Name
  • Potassium Voltage-Gated Channel Subfamily H Member 2
  • Introduction
  • This gene encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified.
  • Alternative Names
  • Potassium Voltage-Gated Channel Subfamily H Member 2; Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 2; Ether-A-Go-Go-Related Gene Potassium Channel 1; Voltage-Gated Potassium Channel Subunit Kv11.1; Ether-A-Go-Go-Related Protein 1; Eag-Related Protein 1; Eag Homolog; ERG-1; HERG1; H-ERG

Case Studies

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