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NativeExtract™ Recombinant Full Length Human TRPV4 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW162)

This product is recombinant Human TRPV4 protein in native nanodisc form. The synthetic compound we developed can solubilize the TRPV4 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TRPV4
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 98.3 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • TRPV4
  • Full Name
  • Transient Receptor Potential Cation Channel Subfamily V Member 4
  • Introduction
  • This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • Transient Receptor Potential Cation Channel Subfamily V Member 4; Osmosensitive Transient Receptor Potential Channel 4; Transient Receptor Potential Protein 12; Vanilloid Receptor-Like Channel 2; Osm-9-Like TRP Channel 4; OTRPC4; TRP12; VROAC; VRL2; Transient Receptor Potential Cation Channel, Subfamily V, Member 4; Vanilloid Receptor-Related Osmotically Activated Channel; Vanilloid Receptor-Related Osmotically-Activated Channel

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