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NativeExtract™ Recombinant Full Length Human TRPC6 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW192)

This product is recombinant Human TRPC6 protein in native nanodisc form. The synthetic compound we developed can solubilize the TRPC6 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TRPC6
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 106.3 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • TRPC6
  • Full Name
  • Transient Receptor Potential Cation Channel Subfamily C Member 6
  • Introduction
  • The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).
  • Alternative Names
  • Transient Receptor Potential Cation Channel Subfamily C Member 6; Focal Segmental Glomerulosclerosis 2; Transient Receptor Protein 6; TRP-6; TRP6; Transient Receptor Potential Cation Channel, Subfamily C, Member 6; Short Transient Receptor Potential Channel 6; FSGS2; TrpC6

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