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NativeExtract™ Recombinant Full Length Human TRPV6 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW137)

This product is recombinant Human TRPV6 protein in native nanodisc form. The synthetic compound we developed can solubilize the TRPV6 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TRPV6
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 87.3 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • TRPV6
  • Full Name
  • Transient Receptor Potential Cation Channel Subfamily V Member 6
  • Introduction
  • This gene encodes a member of a family of multipass membrane proteins that functions as calcium channels. The encoded protein contains N-terminal ankyrin repeats, which are required for channel assembly and regulation. Translation initiation for this protein occurs at a non-AUG start codon that is decoded as methionine. This gene is situated next to a closely related gene for transient receptor potential cation channel subfamily V member 5 (TRPV5). This locus has experienced positive selection in non-African populations, resulting in several non-synonymous codon differences among individuals of different genetic backgrounds.
  • Alternative Names
  • Transient Receptor Potential Cation Channel Subfamily V Member 6; Epithelial Calcium Channel 2; Calcium Transport Protein 1; ECAC2; CAT1; Transient Receptor Potential Cation Channel, Subfamily V, Member 6; Epithelial Apical Membrane Calcium Transporter/Channel CaT1; Alu-Binding Protein With Zinc Finger Domain; Calcium Transporter-Like Protein

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