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Recombinant Human ADORA2A Full-Length Membrane Protein, MNP (CAT#: SYF-0826-CW26)

This product contains recombinant full-length human ADORA2A expressed in HEK293 cells and presented in a membrane nanoparticle format with a C-terminal Flag tag.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ADORA2A
  • Protein Length
  • 412 aa
  • Protein Class
  • Class A G protein-coupled receptor
  • Molecular Weight
  • 44.7 kDa
  • TMD
  • 7

Product Description

  • Activity
  • Validated by ELISA; antibody-binding EC50: 6.796 ng/mL.
  • Application
  • ELISA; Flow cytometry; Antibody binding and screening studies
  • Expression Systems
  • HEK293 expression system
  • Tag
  • C-Terminal Flag Tag
  • Protein Format
  • Membrane Nanoparticle (MNP)
  • Buffer
  • PBS, pH 7.4, with 5-8% trehalose as a lyoprotectant

Target

  • Target Protein
  • ADORA2A
  • Full Name
  • adenosine A2a receptor
  • Introduction
  • ADORA2A is a Gs-coupled adenosine receptor that increases intracellular cAMP. It regulates cardiovascular, neurological and immune functions and is an important immuno-oncology target.
  • Alternative Names
  • A2aR; ADORA2; RDC8

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