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The 5.7 kDa polypeptide hormone insulin is structured as two polypeptide chains, the 21 amino acid A chain and the 30 amino acid B chain, linked by two disulphide bonds. Insulin is synthesized in the beta cells of the islets of Langerhans in the pancreas as a prohormone; proinsulin that is later transformed by proteolytic action into the active hormone. Insulin excerts multiple actions throughout the body to regulate the energy metabolism. Its anabolics action includes build-up and storage of glycogen and fat.
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