Human LBP Protein (Ala 26-Val 481) [His] (VAng-1879Lsx)
Human Lipopolysaccharide (LBP) protein, His tag, expressed in human 293 cells. (Uniprot ID: P18428)
Datasheet
Specifications
Source
HEK293 Cells.
Target
LBP
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
PBS, pH 7.4.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
LBP (Lipopolysaccharide Binding Protein) is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP).
Alternative Names
Lipopolysaccharide-binding protein, LBP
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