Human LILRB1 Protein (Gly 24-His 458) [Fc] (VAng-1887Lsx)
Human LILRB1 protein, Fc tag, expressed in human 293 cells. (Uniprot ID: NP_006660)
Datasheet
Specifications
Source
HEK293 Cells.
Target
LILRB1
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
50 mM Tris, 100 mM Glycine, pH 7.5.
Purity
> 92% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
LILRB1 (Leukocyte Immunoglobulin Like Receptor B1) is a member of the leukocyte immunoglobulin-like receptor (LIR) family. The protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity.
Alternative Names
CD85J, LILRB1, CD85, ILT2, LIR1, MIR7
Related Product
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