Human LILRB4 Protein (Gln 22-Glu 259) [human IgG1 Fc tag] (VAng-1893Lsx)
Human LILRB4 protein, human IgG1 Fc tag, expressed in human 293 cells. (Uniprot ID: AAH26309)
Applications
SDS-PAGE; WB; ELISA.
Formulation
50 mM Tris, 100 mM Glycine, pH 7.5.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Introduction
LILRB4 (Leukocyte Immunoglobulin Like Receptor B4) is a member of the leukocyte immunoglobulin-like receptor (LIR) family. The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity.
Alternative Names
LILRB4, ILT3, LIR5, CD85K, HM18
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