Human LOXL2 Protein (Gln 26-Gln 774) [His] [Avi] (VAng-1898Lsx)

Human LOXL2 protein, His tag and Avi tag, expressed in human 293 cells. (Uniprot ID: Q9Y4K0-1)

Datasheet

Specifications

Source

HEK293 Cells.

Target

LOXL2

Type

Tumor Antigens

Applications

SDS-PAGE; WB; ELISA.

Formulation

PBS, pH 7.4.

Purity

> 95% pure by SDS-PAGE.

Storage

Store at -20°C to -80°C.

Antigen Information

Introduction

LOXL2 (Lysyl Oxidase Like 2) is a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.

Alternative Names

Lysyl oxidase homolog 2, LOXL2