Human Nectin-4 Protein (Gly 32-Ser 349) [His] (VAng-2593Lsx)

Human Nectin-4 protein, His tag, was expressed in human 293 cells. (Uniprot ID: Q96NY8-1)

Datasheet

Specifications

Source

HEK293 cells

Target

Nectin-4

Type

Tumor Antigens

Applications

SDS-PAGE; WB; ELISA.

Formulation

PBS, pH 7.4.

Purity

> 95% pure by SDS-PAGE.

Storage

Store at -20°C to -80°C.

Antigen Information

Introduction

NECTIN4 (Nectin Cell Adhesion Molecule 4) contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder.

Alternative Names

NECTIN4, LNIR, PRR4, PVRL4