Human Neuroligin 1 Protein (Phe 22-Lys 644) [His] (VAng-2603Lsx)
Human Neuroligin 1 (NRP1) protein, His tag, was expressed in human 293 cells. (Uniprot ID: AAH07533)
Datasheet
Specifications
Source
HEK293 cells
Target
NRP1
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
PBS, pH 7.4.
Purity
> 92% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
NRP1 (Neuropilin 1) participates in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Diseases associated with NRP1 include Angiomatous Meningioma and Neuroma.
Alternative Names
NRP1, Neuropilin-1, NRP, VEGF165R, CD304
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