Human TNFRSF11B Protein (Glu 22-Leu 401) [Fc] (VAng-2626Lsx)
Human Osteoprotegerin protein, human IgG1 Fc tag, was expressed in human 293 cells. (Uniprot ID: NP_002537)
Datasheet
Specifications
Source
HEK293 cells
Target
TNFRSF11B
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
50 mM Tris, 100 mM Glycine, pH 7.5.
Purity
> 92% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
TNFRSF11B (TNF Receptor Superfamily Member 11b) is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification.
Alternative Names
TNFRSF11B, OCIF, OPG, Osteoprotegerin
Related Product
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