Biotinylated Human CX3CL1 Protein (Gln 25-Gln 341) [His] (VAng-1439Lsx)
Biotinylated Human CX3CL1, His tag, is expressed in HEK 293 cells. (Uniprot ID: AAH01163)
Applications
SDS-PAGE; WB; ELISA.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Introduction
CX3CL1 (C-X3-C Motif Chemokine Ligand 1) contains an extended mucin-like stalk with a chemokine domain on top, and exists in both a membrane-anchored form where it acts as a binding molecule, or, in soluble form, as a chemotactic cytokine. The mature form of this protein can be cleaved at the cell surface, yielding different soluble forms that can interact with the G-protein coupled receptor, C-X3-C motif chemokine receptor 1 gene product. This gene plays a role in a wide range of diseases, including cancer, vasculitis, neuropathies, atherosclerosis, inflammatory diseases, and in human immunodeficiency virus infections.
Alternative Names
CX3CL1, Fractalkine
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