Recombinant CXCR4 Protein (Met 1-Ser 46) [Fc] (VAng-1441Lsx)
Human CXCR4 (CD184), Fc tag, is expressed in HEK 293 cells. (Uniprot ID: AAH20968.1)
Applications
SDS-PAGE; WB; ELISA.
Formulation
50 mM Tris, 100 mM Glycine, pH 7.5.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Introduction
CXCR4 (C-X-C Motif Chemokine Receptor 4) a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM syndrome.
Alternative Names
CXCR4, CD184, Fusin, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM
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