IL-18BP

IL18BP (Interleukin 18 Binding Protein) functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Diseases associated with IL18BP include Gillessen-Kaesbach-Nishimura Syndrome and Crohn's Disease.

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-1794Lsx Human IL-18BP Protein (Thr 31-Gly 194) [Fc] HEK293 Cells. Human IL-18BP, Fc tag, is expressed in human 293 cells. (Uniprot ID: NP_001138529) IL-18BP Tumor Antigens Datasheet 100 µg Inquiry
VAng-1795Lsx Human IL-18BP Protein (Thr 31-Gly 194) [His] HEK293 Cells. Human IL-18BP, His tag, is expressed in human 293 cells. (Uniprot ID: NP_001138529) IL-18BP Tumor Antigens Datasheet 100 µg Inquiry

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