Human IL-18BP Protein (Thr 31-Gly 194) [His] (VAng-1795Lsx)
Human IL-18BP, His tag, is expressed in human 293 cells. (Uniprot ID: NP_001138529)
Datasheet
Specifications
Source
HEK293 Cells.
Target
IL-18BP
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
PBS, pH 7.4.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
IL18BP (Interleukin 18 Binding Protein) functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Diseases associated with IL18BP include Gillessen-Kaesbach-Nishimura Syndrome and Crohn's Disease.
Alternative Names
IL18BP, IL18BPa, Tadekinig-alfa
Related Product
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