Thrombin

F2 (Coagulation Factor II, Thrombin) is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia.

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-1410Lsx Recombinant Coagulation Factor II Protein (Gln 25-Glu 622) [His] HEK293 Cells. Human Coagulation Factor II (thrombin), His tag, is expressed in HEK 293 cells. (Uniprot ID: AAH51332) Thrombin Tumor Antigens Datasheet 50 µg Inquiry

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