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NativeExtract™ Recombinant Full Length Human ACHE Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW68)

This product is recombinant Human ACHE protein in native nanodisc form. The synthetic compound we developed can solubilize the ACHE protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ACHE
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 54.7 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • ACHE
  • Full Name
  • Cholinergic Receptor Nicotinic Epsilon Subunit
  • Introduction
  • Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome.
  • Alternative Names
  • Cholinergic Receptor Nicotinic Epsilon Subunit; Acetylcholine Receptor, Nicotinic, Epsilon (Muscle); Cholinergic Receptor, Nicotinic, Epsilon (Muscle); Cholinergic Receptor, Nicotinic Epsilon; ACHRE; Cholinergic Receptor, Nicotinic, Epsilon Polypeptide; Cholinergic Receptor, Nicotinic, Epsilon; Acetylcholine Receptor Subunit Epsilon; AchR Epsilon Subunit

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