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NativeExtract™ Recombinant Full Length Human GRIA1 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW144)

This product is recombinant Human GRIA1 protein in native nanodisc form. The synthetic compound we developed can solubilize the GRIA1 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GRIA1
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 101.5 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • GRIA1
  • Full Name
  • Glutamate Ionotropic Receptor AMPA Type Subunit 1
  • Introduction
  • Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • Glutamate Ionotropic Receptor AMPA Type Subunit 1; Glutamate Receptor, Ionotropic, AMPA 1; AMPA-Selective Glutamate Receptor 1; GluR-K1; GluR-1; GluR-A; GLUR1; GLUH1

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