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MemDX™ Recombinant Full Length Human AQP1 Protein (Nanodisc, Rho1D4 Tag) (CAT#: SYF-0926-CW40)

Recombinant full-length human AQP1 protein reconstituted in a nanodisc membrane-mimetic system for biochemical, binding, and assay development applications.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • AQP1
  • Protein Length
  • Full-length
  • Protein Class
  • Aquaporin
  • Molecular Weight
  • 29 kDa (homotetramer)
  • Sequence
  • MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTDRVKVWTSGQVEEYDLDADDINSRVEMKPK

Product Description

  • Expression Systems
  • HEK293 cells
  • Tag
  • The construct includes a C-terminal Rho1D4 tag.
  • Protein Format
  • Nanodisc
  • Purity
  • The protein purity is greater than 90% as determined by SDS-PAGE.

Target

  • Target Protein
  • AQP1
  • Full Name
  • aquaporin 1
  • Introduction
  • Aquaporin-1 (AQP1) is a full-length human aquaporin. Aquaporin-1 is a protein involved in water homeostasis in several tissues by forming a water channel that allows passive transport of water along the osmotic gradient. It is implicated in the inter- and intracellular transport of water and is mainly expressed in the kidney. AQP1 may be associated with various health conditions, such as ocular fluid movement, but it could also be a prognostic marker for various types of cancer, as AQP1 has been shown to regulate tumour cell migration, cell-cell adhesion and angiogenesis, among other things, and is thus involved in cancer progression. The protein is supplied in an MSP-free, copolymer-stabilized native-lipid nanodisc. The preparation uses 2-step purification.
  • Alternative Names
  • CHIP28, CO

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