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NativeExtract™ Recombinant Full Length Human CAC1B Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW211)

This product is recombinant Human CAC1B protein in native nanodisc form. The synthetic compound we developed can solubilize the CAC1B protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CAC1B
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 262.5 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • CAC1B
  • Full Name
  • Calcium Voltage-Gated Channel Subunit Alpha1 B
  • Introduction
  • The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • Calcium Voltage-Gated Channel Subunit Alpha1 B; Calcium Channel, Voltage-Dependent, N Type, Alpha 1B Subunit; Voltage-Gated Calcium Channel Subunit Alpha Cav2.2; Brain Calcium Channel III; CACNL1A5; BIII; Calcium Channel, Voltage-Dependent, L Type, Alpha 1B Subunit; Voltage-Dependent N-Type Calcium Channel Subunit Alpha-1B; Calcium Channel, L Type, Alpha-1 Polypeptide Isoform 5

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