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NativeExtract™ Recombinant Full Length Human GPRC5D Protein (Petitide Nanodisc, FLAG-tagged) (CAT#: SYF-0426-CW306)

This product is recombinant Human GPRC5D protein in peptide nanodisc form. The synthetic peptide scaffold we developed can solubilize the GPRC5D protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GPRC5D
  • Protein Length
  • Full length
  • Protein Class
  • GPCR; Checkpoint
  • Molecular Weight
  • 38.8 kDa
  • Sequence
  • Our product features full-length membrane proteins with complete, native sequences, ensuring optimal structural integrity and functional activity for your research needs.

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • GPRC5D
  • Full Name
  • G protein-coupled receptor class C group 5 member D
  • Introduction
  • GPCR5D belongs to the G protein-coupled receptor (GPCR) family. Recent studies show that GPRC5D is expressed on malignant bone marrow plasma cells, while its expression in normal tissues is confined to the hair follicle. It may serve as a potential target for effector-cell-mediated therapies in treating plasma-cell disorders, such as multiple myeloma .

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