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NativeExtract™ Recombinant Full Length Human KCIP2 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW217)

This product is recombinant Human KCIP2 protein in native nanodisc form. The synthetic compound we developed can solubilize the KCIP2 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KCIP2
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 30.9 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • KCIP2
  • Full Name
  • Potassium Voltage-Gated Channel Interacting Protein 2
  • Introduction
  • This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified from this gene.
  • Alternative Names
  • Potassium Voltage-Gated Channel Interacting Protein 2; Cardiac Voltage-Gated Potassium Channel Modulatory Subunit; A-Type Potassium Channel Modulatory Protein 2; Potassium Channel-Interacting Protein 2; Kv Channel-Interacting Protein 2; KCHIP2; Kv Channel Interacting Protein 2

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